Possible side effects of Leukeran

Consumer Information (MedFacts)

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Agitation; clumsiness; confusion; diarrhea; tingling or numbness in the hands and feet; tiredness; tremors; twitching.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); absence of monthly period; chills; congestion; excessive tiredness; fever; hallucinations; hip, stomach, or joint pain; infertility; nausea; persistent cough; seizures; shortness of breath or difficulty breathing; sore throat; sores in the mouth or on the lips; unusual bruising or bleeding; unusual lumps or masses; vomiting; yellowing of the skin or eyes.

This is not a complete list of all side effects that may occur. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

Advanced Consumer Information (Micromedex)

• seizure (convulsions);

• fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;

• nausea, stomach pain, low fever, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);

• an unusual mass or lump;

• fever, chills, body aches, flu symptoms, or ongoing cough;

• pale skin, easy bruising or bleeding, unusual weakness;

• white patches or sores inside your mouth or on your lips;

• severe nausea, vomiting, or diarrhea; or

• missed menstrual periods.

Keep taking chlorambucil and talk to your doctor if you have any of these less serious side effects:

• upset stomach, mild nausea, diarrhea;

• tremors or shaking; or

• numbness or tingling.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems or unusual or that is especially bothersome.

Consumer Information (Cerner Multum)

Along with its needed effects, a medicine may have some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Discuss these possible effects with your doctor.

Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

After you stop using chlorambucil, it may still produce some side effects that need attention. During this period of time, check with your doctor if you notice any of the following side effects:

Black, tarry stools; blood in urine or stools; cough or hoarseness (may be accompanied by fever or chills); fever or chills; lower back or side pain, accompanied by fever or chills; painful or difficult urination, accompanied by fever or chills; pinpoint red spots on skin; shortness of breath; unusual bleeding or bruising

Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.