Leukeran

Leukeran

Leukeran is used for:

Treating certain cancers. It may also be used to treat other conditions as determined by your doctor.

Leukeran is an alkylating agent. It works by binding to the RNA or DNA of certain cancer cells, which helps to slow down their growth and reproduction.

Do NOT use Leukeran if:

• you are allergic to any of the ingredients contained in Leukeran
• you are in the first trimester of pregnancy

Contact your health care provider as soon as possible if any of the above applies to you.

Consider before using Leukeran

Medical Conditions

There are medical conditions that can influence usage of Leukeran . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are either pregnant or planning to become pregnant
• if you are breast-feeding
• if you are taking any medicine (either prescription or nonprescription), herbal preparation, or dietary supplement
• if you have allergies to medicines, foods, or other substance
• if you are receiving or have recently completed radiation therapy, suffer from bone marrow depression, have decreased white blood counts or decreased blood platelets, an infection, shingles, chickenpox, or the blood disease porphyria
• if you have had an allergic reaction to any other alkylating agent (eg, cyclophosphamide)
• if you have kidney disease, or a history of seizures or head trauma

Drugs Interaction

There are medicines that may interact with Leukeran . However, no specific interactions with Leukeran are known at this time.

This is not a full list of all interactions that may occur. Clarify with your health care provider whether Leukeran may interact with other medicines you take. Also, consult your health care provider in advance if you are going to start, stop, or change the dose of any medicine.

Leukeran Usage Guidelines

You should use Leukeran as recommended by your doctor. Read the medicine's label for precise dosing instructions.

• Leukeran may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.
• Leukeran is the most effective when taken at the same time every day.
• Drinking extra fluids while you are taking Leukeran is recommended.
• If you miss a dose of Leukeran and take 1 dose daily, take the missed dose if you remember the same day. Skip the dose if you do not remember until the next day. Do not take 2 doses at the same time.

Ask your health care provider any questions you may have about how to use Leukeran .

Important safety information on leukeran

• Leukeran may cause drowsiness. Do not drive, operate machinery, or do anything else that could be dangerous until you know how you react to Leukeran . Using Leukeran alone, with certain other medicines, or with alcohol may lessen your ability to drive or to perform other potentially dangerous tasks.
• If nausea, vomiting, or loss of appetite occurs, ask your doctor, nurse, or pharmacist for ways to lessen these effects.
• Leukeran may reduce the number of blood cells that are needed for clotting. To prevent bleeding, avoid situations where bruising or injury may occur.
• Leukeran may lower your body's ability to fight infection. To prevent infection, avoid contact with people who have colds or other infections. Do not touch your eyes or the inside of your nose unless you have thoroughly washed you hands first.
• The use of birth control is recommended while you are taking Leukeran .
• Check with your doctor before having immunizations (vaccinations) while you are using Leukeran .
• LAB TESTS, such as complete blood counts, may be performed to monitor your progress or to check for side effects. Be sure to keep all doctor and lab appointments.
• Use Leukeran with caution in CHILDREN with kidney disease. They may have an increased risk of seizures.
• PREGNANCY and BREAST-FEEDING: Leukeran has been shown to cause harm to the fetus. Avoid becoming pregnant while taking Leukeran . If you become pregnant, discuss with your doctor the benefits and risks of using Leukeran during pregnancy. It is unknown if Leukeran is excreted in breast milk. Do not breast-feed while taking Leukeran .

Side effects may be caused by Leukeran

All medicines may cause side effects, but many people have no, or minor, side effects. Consult your doctor if any of the most COMMON side effects from the list below persist or start bothering you:

Agitation; clumsiness; confusion; diarrhea; tingling or numbness in the hands and feet; tiredness; tremors; twitching.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); absence of monthly period; chills; congestion; excessive tiredness; fever; hallucinations; hip, stomach, or joint pain; infertility; nausea; persistent cough; seizures; shortness of breath or difficulty breathing; sore throat; sores in the mouth or on the lips; unusual bruising or bleeding; unusual lumps or masses; vomiting; yellowing of the skin or eyes.

It sholud be noted, that this is not a full list of possible side effects. If you have questions or need medical advice about side effects, contact your doctor or health care provider. You may report side effects to the FDA at 1-800-FDA-1088 (1-800-332-1088) or at http://www.fda.gov/medwatch.

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center (http://www.aapcc.org/findyour.htm), or emergency room immediately. Symptoms may include agitation; dizziness; impaired coordination; seizures.

Leukeran storage instructions:

Store Leukeran in the refrigerator, between 36 and 46 degrees F (2 and 8 degrees C). Keep Leukeran out of the reach of children and away from pets.

General information:

• If you have any questions on Leukeran , please consult your doctor, pharmacist, or health care provider.
• Leukeran is supposed to be used only by the patient it is prescribed to. Do not share it with other people.
• If your symptoms do not improve or even become worse, inform your doctor.

This article is a summary only, and it does not provide all the information about Leukeran . If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

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